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A Brief History of Vaccination Associated Sarcomas 

1985

Modified Live non adjuvanted Rabies vaccines were withdrawn from the market and replaced with adjuvanted killed rabies vaccines.

1985

The first Feline Leukemia vaccine was introduced which contained aluminum adjuvant

1987

Most States in the U.S. adopted their first mandatory rabies vaccine ordinance for cats

1988

Scientists noticed an increase in the number of VAS in cats and the first study was started

1991

The first report associating vaccination and the subsequent fibrosarcoma Heinrich in the Journal of the American Veterinary Medical Association published development at the injection site

1992

Henrich reported the association of injection site reactions and fibrosarcomas in the Journal of Cancer Research. Aluminum Adjuvant was identified in the tumors

1993

Kass study showed that the risk of VAS increases with the number of vaccines administered

1995

Journal of the American Veterinary Association In an article entitled “Are we Vaccinating Too Much?” Nine Veterinary Immunologist advocate change

1995

Dennis Macy demonstrated the role of inflammation caused by vaccines in the development of VAS. Testing of vaccines showed adjuvanted vaccines caused more inflammation than non-adjuvanted vaccines.  Sem Vet Med Surg S A

1996

The Vaccine Associated Feline Sarcoma Task Force was formed providing over $700 thousand dollars in funding for research.

1996

Burton published in the Australian Vet Journal that fibrosarcomas are rare in Australia, citing that they do not vaccinate for rabies as they have no rabies in Australia, and that they do not have an adujvanted Feline leukemia vaccine on the market

1997

Heska introduces intranasal vaccines. No only is the mucosal immunity for RhCv better, there is no potential for VAS formation.

1998

The American Association of Feline Practitioners completed their new feline vaccination recommendations.

1998

The AVMA Council on Biologic and Therapeutic Agents sends a policy statement to they USDA CVB: There is no Scientific Data to support label claims to administer MLV vaccines annually. Label claims should be backed by scientific data.

1998

McNeil demonstrated that adjuvnated rabies vaccines induced mutations on cell cultures. 18th ACVIM

1999

Dr Ron Schultz demonstrated that once a pet has been immunized; repeat administration of MLV vaccines has no effect. The immune status of the pet is not

1999

Muriel introduces a non adjuvanted rabies vaccine Purevac. Testing by Dennis Macy showed no tissue inflammation and therefor less risk of VAS formation

2000

The World Health Organization, Lyons, France declared adjuvanted vaccines to be carcinogens for cats.

2000

The American Association of Feline Practitioners updates their vaccination recommendations

2001

Mc Neil demonstrated that adjuvanted vaccines induced mutations on cell cultures and non adjuvanted vaccines did not.

   


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